Radiomic Features From Multi-Parameter MRI Combined With Clinical Parameters Predict Molecular Subgroups in Patients With Medulloblastoma
نویسندگان
چکیده
منابع مشابه
MRI surrogates for molecular subgroups of medulloblastoma.
BACKGROUND AND PURPOSE Recently identified molecular subgroups of medulloblastoma have shown potential for improved risk stratification. We hypothesized that distinct MR imaging features can predict these subgroups. MATERIALS AND METHODS All patients with a diagnosis of medulloblastoma at one institution, with both pretherapy MR imaging and surgical tissue, served as the discovery cohort (n =...
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15 صفحه اولSignaling pathway and molecular subgroups of medulloblastoma.
Medulloblastoma (MB) is the most common malignant brain tumor in children. Although multimodality treatment regimens including surgery, radiotherapy and chemotherapy have greatly improved disease outcome, about one-third of MB patient remains incurable, and many long-term survivors are suffered from deleterious effects due to aggressive treatment. Understanding the signaling pathways and the ge...
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ژورنال
عنوان ژورنال: Frontiers in Oncology
سال: 2020
ISSN: 2234-943X
DOI: 10.3389/fonc.2020.558162